SEKISUI XenoTech offers cytokine release and hazard identification assays

Is your drug a #cytokine modulator? We offer #invitro cytokine release and hazard identification assays to evaluate the potential of a #biologic or #smallmolecule #drug to cause a drug- #druginteraction (DDI) directly or through cytokine effect on the expression of drug-metabolizing enzymes and/or #drugtransporters. Our experts can evaluate direct and indirect (cytokine-mediated) effects using co-cultures containing fresh human #hepatocytes and #Kupffer cells using a specialized assay patented by our R&D team. Following treatment, transporter and/or #cytochrome #P450 enzymatic activity is measured and change in expression levels is quantified by qRT-PCR analysis. Find more information and reach out to a service specialist to book a study: https://lnkd.in/gdkPBEG